CONTENT OF PHOSPHATES AND METHEMOGLOBIN IN ERYTHROCYTES OF PATIENTS WITH ISCHEMIC-HEART-DISEASE

Cardiac insufficiency due to chronic ischemic heart disease is accompanied by a reduction of total phosphate at the expense of its organic part with a simultaneous increase of the role of inorganic phosphate during increase of methemoglobin in the erythrocytes. After traditional therapy the methemoglobin level continued to rise while inorganic phosphate and the level of 2,3-DPH decreased. Treatment including myldronate caused an increase of 2,3-DPH in erythrocytes and a decrease of methemoglobin indicating an improvement of the oxygentransport function of the blood.