SYNTHESIS AND ANTIINFLAMMATORY ACTIVITY OF INDOLE CARBOXYLIC-ACIDS AND ESTERS

被引：0

作者：

ANDREANI, A ^{[1
]}

RAMBALDI, M ^{[1
]}

LOCATELLI, A ^{[1
]}

CONTI, M ^{[1
]}

MALANDRINO, S ^{[1
]}

机构：

[1] INVERNI BEFFA SPA,I-20141 MILAN,ITALY

来源：

ACTA PHARMACEUTICA NORDICA | 1991年 / 3卷 / 01期

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

1-Phenylalkylindole-3-carboxylic acids 1-4, indole-1-acetic acids/esters 5-10 and the hydrazones 11-15 were prepared and submitted to the rat paw edema test using carrageenin. In the first two groups of compounds, the 2-chloro indoles were more active than the corresponding indole derivatives. In the third group the activity seemed to be determined largely by the substituent at the 1-position.

引用

页码：5 / 8

页数：4

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