Secondary Lymphoma in a Patient with a History of Unilateral Retinoblastoma

被引：0
|
作者：
Kozanoglu, Banu [1 ]
Sezgin, Gulay [1 ]
Bagir, Emine
Ozkan, Ayse [1 ]
Bayram, Ibrahim [1 ]
Tanyeli, Atila [1 ]
Kupeli, Serhan [1 ]
机构：
[1] Cukurova Univ, Fac Med, Dept Pediat Oncol, Pediat Bone Marrow Transplantat Unit, Adana, Turkey
来源：
CUKUROVA MEDICAL JOURNAL | 2015年 / 40卷
关键词：
lymphoma; retinoblastoma; second neoplasm; children;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Second malignancies develop with increased incidence in patients with herediter retinoblastoma. The most common second malignancies in retinoblastoma survivors are soft tissue sarcoma and osteosarcoma. Lymphoma developing as a second malignancy has rarely been reported. Here we report a case of lymphoma diagnosed in a 13 year-old-boy, 12 years after the diagnosis of unilateral retinoblastoma having heterozygous p.R552 (c.1654C>T) mutation, treated with enucleation and radiotherapy. The risk of second tumour is higher in the hereditary retinoblastoma, especially in cases undergoing external beam radiation therapy.
引用
收藏
页码：33 / 37
页数：5
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