NUCLEOTIDE-SEQUENCE OF THE URA1 GENE OF SACCHAROMYCES-CEREVISIAE

被引：15
|
作者：
ROY, A
机构：
[1] C.N.R.S. U.P.R. 9003 Cancerogenese et Mutagenese Moleculaire et Structurale, Institut de Biologie Moléculaire et Cellulaire
来源：
GENE | 1992年 / 118卷 / 01期
关键词：
DIHYDROOROTIC ACID DEHYDROGENASE ACTIVITY; PYRIMIDINE PATHWAY; PYRIMIDINE PATHWAY REGULATOR-1 CONTROL; RECOMBINANT DNA;
D O I：
10.1016/0378-1119(92)90265-Q
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The complete nucleotide sequence of the URA1 gene encoding dihydroorotic acid dehydrogenase (DHOdehase) is presented. This enzyme catalyses the conversion of DHO to orotic acid and plays a major role in the pyrimidine pathway, as DHO is the effector of the positive control of the transcription of at least four genes, URA1, URA3, URA4 and URA10. Comparisons between the amino acid sequence of the yeast DHOdehase and sequences of DHOdehases previously isolated from Dictyostellum discoidum, Escherichia coli and Bacillus subtilis reveal no obvious homologies.
引用
收藏
页码：149 / 150
页数：2
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