Platelet-Rich Plasma Augmentation in Rotator Cuff Surgery: State of Art

被引:0
|
作者
Longo, Umile Giuseppe [1 ,2 ]
Loppini, Mattia [1 ,2 ]
Berton, Alessandra [1 ,2 ]
Maffulli, Nicola [3 ]
Denaro, Vincenzo [1 ,2 ]
机构
[1] Campus Biomed Univ, Dept Orthopaed & Trauma Surg, Via Alvaro Fortino 200, I-00128 Rome, Italy
[2] Campus Biomed Univ, CIR, Rome, Italy
[3] Mile End Hosp, Barts & London Sch Med & Dent, Ctr Sports & Exercise Med, London, England
关键词
platelet-rich plasma; tendon; stem cells; rotator cuff; sports; athlete;
D O I
10.1053/j.oto.2011.10.003
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Platelet-rich plasma (PRP) may influence tendon healing thanks to the role of platelets in chemotaxis, inflammation, and angiogenesis. Biological properties of PRP may vary as a consequence of different composition characteristics. PRP healing potentiality has been analyzed in animal studies on tendinopathy. However, the rotator cuff model has never been used. In contrast, PRP has been used in clinical studies to enhance the healing process after repair procedure of rotator cuff tears. To date, only 3 randomized controlled trials have been performed. Further randomized controlled trials are necessary to demonstrate PRP clinical benefits. (C) 2012 Elsevier Inc. All rights reserved.
引用
收藏
页码:86 / 90
页数:5
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