THE CONVERSION OF ALPHA-HYDROXY ESTERS TO BETA-HYDROXY ESTERS BY A DEOXYGENATION CONDENSATION REACTION PROMOTED BY SAMARIUM DIIODIDE

被引：21
|
作者：
ENHOLM, EJ
JIANG, SJ
机构：
[1] Department of Chemistry, University of Florida, Gainesville
来源：
TETRAHEDRON LETTERS | 1992年 / 33卷 / 03期
基金：
美国国家科学基金会;
关键词：
SAMARIUM DIIODIDE; DEOXYGENATION; KETYL; BETA-ALKOXY ESTER;
D O I：
10.1016/S0040-4039(00)74119-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A mild reaction sequence begins by transforming an alpha-hydroxy ester to an alpha-benzoate ester. Next, the alpha-benzoate ester is both reductively deoxygenated with samarium diiodide and subsequently condensed with a ketone present in the reaction mixture to afford a beta-hydroxy ester with two new alkyl appendages.
引用
收藏
页码：313 / 316
页数：4
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