STOCHASTIC-ANALYSIS OF DISPERSION IN SIZE-EXCLUSION CHROMATOGRAPHIC COLUMNS

被引:0
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作者
ADROVER, A
BARBA, D
GIONA, M
SPERA, D
机构
[1] UNIV LAQUILA,DIPARTIMENTO INGN CHIM,I-67040 LAQUILA,ITALY
[2] CONSORZIO RIC APPLICATE BIOTECHNOL,I-67051 AVEZZANO,ITALY
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中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Dispersion properties of biomolecules in size-exclusion chromatographic columns are analyzed both experimentally and theoretically. In order to explain tile linear behaviour of the dispersion coefficient with tile solute velocity, experimentally found for most of the biomolecules considered, a stochastic model of solute dispersion is proposed based on the exit-time equation.
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页码:373 / 382
页数:10
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