ISOENZYMES OF ALKALINE-PHOSPHATASES IN SEMINOMAS - AN IMMUNOHISTOCHEMICAL AND BIOCHEMICAL-STUDY

被引：8
|
作者：
BREHMERANDERSSON, E
LJUNGDAHLSTAHLE, E
KOSHIDA, K
YAMAMOTO, H
STIGBRAND, T
WAHREN, B
机构：
[1] NATL BACTERIOL LAB,DEPT VIROL,S-10521 STOCKHOLM,SWEDEN
[2] SODER SJUKHUSET,DEPT PATHOL,S-10064 STOCKHOLM,SWEDEN
[3] KANAZAWA UNIV,DEPT UROL,KANAZAWA,ISHIKAWA 920,JAPAN
[4] UMEA UNIV,DEPT PHYSIOL CHEM,S-90187 UMEA,SWEDEN
来源：
APMIS | 1990年 / 98卷 / 11期
关键词：
Alkaline phosphatases; Isoenzymes; Seminomas;
D O I：
10.1111/j.1699-0463.1990.tb05023.x
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Placental alkaline phosphatase (the PLAP-like isoenzyme) and liver alkaline phosphatase (LAP) were demonstrated immunohistochemically by use of monoclonal antibodies in the tumor cells of twelve seminomas and one seminoma metastasis. Intestinal alkaline phosphatase (IAP) was not found. The PLAP-like and LAP enzymes showed high catalytic activities compared to normal testis. This is the first occasion that LAP has been demonstrated by immunochemistry in seminoma cells. The results suggest that demonstration of these tumor enzymes may be useful markers for seminomas in histopathological specimens.
引用
收藏
页码：977 / 982
页数：6
相关论文
共 50 条
  • [1] THE ISOENZYMES OF THE ALKALINE-PHOSPHATASES AND THEIR CANCEROLOGIC BIOCHEMISTRIES PROSPECTS
    JARDILLIER, JC
    [J]. ANNALES DE BIOLOGIE CLINIQUE, 1981, 39 (03) : 115 - 120
  • [2] INTEREST OF THE STUDY OF THE ISOENZYMES OF SERUM ALKALINE-PHOSPHATASES IN HEPATOBILIARY PATHOLOGY
    BOIZARDCALLAIS, F
    HIRSCH, JP
    BARBIER, JP
    [J]. ANNALES DE BIOLOGIE CLINIQUE, 1984, 42 (02) : 149 - 149
  • [3] DESCRIPTION OF A DOSAGE METHOD FOR THE ISOENZYMES OF SERUM ALKALINE-PHOSPHATASES
    EYNARD, JC
    FLACHAIRE, E
    LATER, R
    QUINCY, C
    [J]. ANNALES DE BIOLOGIE CLINIQUE, 1984, 42 (02) : 149 - 150
  • [4] ALKALINE-PHOSPHATASES - NEWER CONCEPTS IN ISOENZYMES AND CLINICAL-APPLICATIONS
    GRIFFITHS, J
    [J]. CLINICS IN LABORATORY MEDICINE, 1989, 9 (04) : 717 - 730
  • [5] ALKALINE-PHOSPHATASES
    TROWSDALE, J
    MARTIN, D
    BICKNELL, D
    CAMPBELL, I
    [J]. BIOCHEMICAL SOCIETY TRANSACTIONS, 1990, 18 (02) : 178 - 180
  • [6] ULTRACYTOCHEMICAL AND BIOCHEMICAL STUDY OF ACID AND ALKALINE-PHOSPHATASES IN HUMAN PROSTATIC CANCER CELL
    ASO, Y
    OKADA, K
    TAKAYASU, H
    TOKUE, A
    YOKOYAMA, M
    KOISO, K
    MURAHASHI, I
    [J]. INVESTIGATIVE UROLOGY, 1972, 9 (04): : 329 - +
  • [7] STRUCTURE OF ALKALINE-PHOSPHATASES
    KIM, EE
    WYCKOFF, HW
    [J]. CLINICA CHIMICA ACTA, 1990, 186 (02) : 175 - 187
  • [8] CARCINOPLACENTAL ALKALINE-PHOSPHATASES
    FISHMAN, WH
    SASAKI, M
    BECKMAN, L
    INGLIS, N
    STOLBACH, L
    [J]. PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1973, 14 (MAR): : 111 - &
  • [9] ORGAN-SPECIFIC AND CROSS-REACTING ISOENZYMES IN HUMAN ALKALINE-PHOSPHATASES
    PANKOVICH, AM
    SCLAMBERG, EL
    STEVENS, J
    [J]. INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY, 1972, 43 (03): : 401 - 409
  • [10] ALKALINE-PHOSPHATASES OF HUMAN LIVER - IMMUNOCHEMICAL STUDY
    KORNGOLD, L
    [J]. INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY, 1976, 50 (03): : 297 - 308
12345