共 20 条
FRAGMENTS OF THE INTERNAL TRANSCRIBED SPACER-1 OF PRE-RIBOSOMAL-RNA ACCUMULATE IN SACCHAROMYCES-CEREVISIAE LACKING 5'-]3' EXORIBONUCLEASE-1
被引:106
|作者:
STEVENS, A
HSU, CL
ISHAM, KR
LARIMER, FW
机构:
关键词:
D O I:
10.1128/jb.173.21.7024-7028.1991
中图分类号:
Q93 [微生物学];
学科分类号:
071005 ;
100705 ;
摘要:
The portion of the internal transcribed spacer 1 found on 20S pre-rRNA accumulates in Saccharomyces cerevisiae lacking 5' --> 3' exoribonuclease 1, showing that an endonucleolytic cleavage at the 3' terminus of 18S rRNA is involved in the 20S pre-rRNA to 18S mature rRNA conversion. Smaller fragments of the spacer sequence are also found. The exoribonuclease may be involved as a cytoplasmic RNase in the hydrolysis of the spacer.
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页码:7024 / 7028
页数:5
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