ACTIVITY OF THE ANTIOXIDANT SYSTEM OF RAT-LIVER UNDER BENZIDINE INTOXICATION AND AFTER ENOMELANIN ADMINISTRATION

被引：0
|
作者：
LOMONOSOVA, EE
PIKULEV, AT
KURCHENKO, VP
机构：
来源：
BIOCHEMISTRY-MOSCOW | 1993年 / 58卷 / 04期
关键词：
ANTIOXIDANT ENZYMES; BENZIDINE; ANTIOXIDANTS;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Benzidine administration in vivo decreased the efficiency of the protective action of the antioxidant system. The total antioxidant activity of rat liver cytosol decreased along with superoxide dismutase and catalase activities. Enomelanin promoted the restoration of superoxide dismutase activity. These results suggest that the toxic effect of benzidine may be due to the impairment of the protective antioxidant mechanisms of liver cells which control free radical-dependent processes.
引用
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页码：374 / 377
页数：4
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