INVIVO NEUTRON-ACTIVATION ANALYSIS OF ORGAN CADMIUM BURDENS - REFERENT LEVELS IN LIVER AND KIDNEY AND THE IMPACT OF SMOKING

被引：9
|
作者：
FRANKLIN, DM
GUTHRIE, CJG
CHETTLE, DR
SCOTT, MC
MASON, HJ
DAVISON, AG
TAYLOR, AJN
机构：
[1] UNIV BIRMINGHAM,SCH PHYS & SPACE RES,BIRMINGHAM B15 2TT,W MIDLANDS,ENGLAND
[2] HLTH & SAFETY EXECUT,OCCUPAT HYG & MED LABS,LONDON NW12 6LN,ENGLAND
[3] BROMPTON HOSP,INST CARDIOTHORAC,LONDON SW3 6HP,ENGLAND
来源：
BIOLOGICAL TRACE ELEMENT RESEARCH | 1990年 / 26-7卷
基金：
英国惠康基金;
关键词：
cadmium and smoking; in vivo neutron activation; industrial cadmium exposure; kidney cadmium; liver cadmium; referent cadmium levels;
D O I：
10.1007/BF02992694
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In vivo neutron activation measurements of liver and kidney cadmium have been mae in 77 exposed workers and 101 referents. Cadmium levels were higher in exposed workers than in referents; both in liver, 25.7 cf. 0.6 μg/g, and kidney, 17.9 cf. 2.7 mg. The 19 referents who never smoked had lower mean organ cadmium burdens than the other referents, the difference achieving statistical significance in the kidney, p<.01. Cigaret smoking was estimated to increase cadmium body burden by 370-140 μg/pack year. These referent cadmium levels are similar to, although slightly below, previous in vivo and autopsy data. © 1990 Humana Press Inc.
引用
收藏
页码：401 / 406
页数：6
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