Histological and Physiological Studies on the Effects of Some Energy Drinks on Male Rats

Consumption of Energy drinks (ED) rich in caffeine has been increasing significantly recently between individuals. Health problems related to caffeine such as reproductive diseases were occurred. Therefore, this research aim to study the histological effects of ED on rats' testis, oxidative profile interfering with organ functions, and the possible reversibility of the produced effects. Adult male rats were divided into five groups, these were; Group1 served as control, Groups 2,3,4 and 5 recieved orally either Red Bull or Power horse for 7 weeks. Groups3 and 4 were left for 2 weeks to recover from energy drinks treatment. Blood samples were taken for determination of serum testosterone and tissue malondialdehyde and reduced glutathione were estimated in homogenised testes. Rat testes in ED treated groups showed degenerated germinal epithelium with interstitial edema, dilated congested blood vessels, decreased glutathione, and increased MDA levels. The mean of serum testosterone was also significantly decreased However, testes of recovery Groups had nearly normal histological structure. on conclusion, ED have an effect on testicular structures and functions which were recovered to almost normal when animals were allowed living without further ED. So it should be taken under restricted precautions.