EXPRESSION OF THE MOUSE REN-2 GENE IN THE SMALL-INTESTINE IS REGULATED BY FOOD-INTAKE

被引:3
|
作者
YI, Z
PETERS, J
GANTEN, D
BADER, M
机构
[1] UNIV HEIDELBERG, GERMAN INST HIGH BLOOD PRESSURE RES, NEUENHEIMER FELD 366, W-6900 HEIDELBERG, GERMANY
[2] UNIV HEIDELBERG, DEPT PHARMACOL, W-6900 HEIDELBERG, GERMANY
[3] MAX DELBRUCK CTR MOLEC MED, O-1115 BERLIN, GERMANY
来源
关键词
RENIN ANGIOTENSIN SYSTEM; INTESTINE; GENE EXPRESSION; STARVATION;
D O I
10.1007/BF00384342
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
The existence of a local renin/angiotensin system in the intestine of mammals is speculative despite the known importance of angiotensin II for water and electrolyte homeostasis. We demonstrate the presence of ren-2 transcripts in the small intestine of DBA/2 mice. The marked expression of the ren-2 gene is blunted tissue-specifically by starvation, corroborating a local renin/angiotensin system in this organ.
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页码:199 / 202
页数:4
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