1-Acetyl-17-{2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}-17-azapentacyclo[6.6.5.0(2,7).0(9,14).0(15,19)] nonadeca-2,4,6,9,11,13-hexaene-16,18-dione

被引：0

作者：

Pakosinska-Parys, Magdalena ^{[1
]}

Kossakowski, Jerzy ^{[1
]}

Struga, Marta ^{[1
]}

机构：

[1] Med Univ Warsaw, Fac Med 1, Dept Med Chem, 3 Oczki St, PL-02007 Warsaw, Poland

来源：

MOLBANK | 2010年 / 03期

关键词：

1-acetyl-17-{2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}-17-azapentacyclo[6.6.5.0(2,7).0 (9,14).0(15,19)]nonadeca-2,4,6,9,11,13-hexaene-16,18-dione; cytotoxicity;

D O I：

10.3390/M697

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The title compound was synthesized by condensation of an oxiran imide derivative with an appropriate amine and its IR, H-1 NMR, C-13 NMR and mass spectroscopic data are reported. The synthesized compound was evaluated for its cytotoxicity and anti-HIV-1 activity in MT-4 cells.

引用

页码：1 / 4

页数：4

共 32 条

[1] 17-Hydroxy-1,8-dimethyl-17-azapenta-cyclo[6.6.5.0(2,7).0(9,14).0(15,19)] nonadeca-2,4,6,9(14),10,12-hexaene-16,18-dione
Miroslaw, Barbara
Koziol, Anna E.
Pakosinska-Parys, Magdalena
Struga, Marta
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O3293 - +
[2] (1S,8R,15S,19R)-17-Benzyl-17-azapenta-cyclo-[6.6.5.0(2,7).0(9,14).0(15,19)]nonadeca-2(7), 3,5,9(14), 10,12-hexaene chloroform monosolvate
Bratko, Lelyzaveta
Ladeira, Sonia
Saffon, Nathalie
Teuma, Emmanuelle
Gomez, Montserrat
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O2881 - +
[3] 16-Oxapentacyclo[6.6.5.0(1,18).0(2,7).0(9,14)]nonadeca-2,4,6,9,11,13,18-heptaen-15-one
Mathew, Eason M.
Sithambaresan, M.
Unnikrishnan, P. A.
Kurup, M. R. Prathapachandra
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2014, 70 : 0114 - +
[4] 8,15-Dioxa-10,13-diazatetracyclo-[14.4.0.0(2,7).0(9,14)]icosa-1(16),2,4,6,9(14),10,12,17,19-nonaene
Srinivasan, Thothadri
Kalpana, Venkatesan
Rajakumar, Perumal
Velmurugan, Devadasan
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2013, 69 : O813 - +
[5] 10 alpha-Hydroxy-13-{[4-(4-methoxyphenyl)-piperazin-1-yl]methyl}-4,9-dimethyl-3,8,15-trioxatetracyclo[10.3.0.0(2,4).0(7,9)]-pentadecan-14-one
Moumou, Mohamed
Benharref, Ahmed
Daran, Jean Claude
Outouch, Rachid
Berraho, Moha
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O715 - U2131
[6] Methyl 11-hydroxy-9-[1-(4-methoxyphenyl)-4-oxo-3-phenylazetidin-2- yl]18-oxo-10-oxa-2- azapentacyclo[9.7.0.0(1,8).0(2,6).0(12,17)] octadeca12 (17), 13,15-triene-8-carboxylate
Suhitha, Sivasubramanian
Srinivasan, Thothadri
Rajesh, Raju
Raghunathan, Raghavachary
Velmurugan, Devadasan
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2013, 69 : O438 - +
[7] Methyl 12-hydroxy-10-[1-(4-methoxyphenyl)-2-oxo-3-phenoxyazetidin-4-yl]11-oxa-3-azahexacyclo[11.7.1.0(2,9).0(2,12).-0(3,7).0(17,21)]henicosa-1(20),13,15,17(21),18-pentaene-9-carboxylate
Suhitha, Sivasubramanian
Srinivasan, Thothadri
Rajesh, Raju
Raghunathan, Raghavachary
Velmurugan, Devadasan
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O3329 - +
[8] 11-Hydroxy-9-[1-(4-methylphenyl)-4-oxo-3-phenylazetidin-2-yl]-18-oxo-10-oxa-2-azapentacyclo-[9.7.0.0(1,8).0(2,6).0(12,17)]octadeca-12,14,16-triene-8-carbonitrile
Suhitha, Sivasubramanian
Srinivasan, Thothadri
Rajesh, Raju
Raghunathan, Raghavachary
Velmurugan, Devadasan
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O3290 - +
[9] 1,3,7,9,11,15,17,19,23,25,27,34-DODECAAZANONACYCLO[25.5.3.2(6,9).2(14,17).2(22,25)1(3,7).1(11,15).1(19,23).0(30,34)]-TETRATETRACONTANE
DALE, J
ROMMING, C
SUISSA, MR
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1995, (16) : 1631 - 1632
[10] 1,3,6,7,9,11,14,15,17,19,22,23,25,27,30,34-HEXADECAAZANONACYCLO[25.5.3.2(6,9).2(14,17).2(22,25).1(3,7).1(11,15).1(19,23).0(30,34)]-TETRATETRACONTANE
DALE, J
ROMMING, C
SUISSA, MR
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1995, (16) : 1633 - 1634

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