SEQUENCE OF AN EXON OF THE FELINE P53 GENE - MUTATION IN A LYMPHOSARCOMA

被引：23

作者：

MAYR, B

HECZKO, U

SCHELLANDER, K

SCHLEGER, W

REIFINGER, M

机构：

[1] VET UNIV VIENNA,LUDWIG BOLTZMANN INST IMMUNO & CYTOGENET RES,A-1030 VIENNA,AUSTRIA

[2] VET UNIV VIENNA,INST PATHOL,A-1030 VIENNA,AUSTRIA

来源：

BRITISH VETERINARY JOURNAL | 1993年 / 149卷 / 04期

关键词：

D O I：

10.1016/S0007-1935(05)80077-6

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Exon 8 of tumour suppressor gene p53 was sequenced in domestic cats and showed remarkable similarity to the human sequence. Only four of the 13 nucleotide differences gave rise to interspecific amino acid differences. In an investigated lymphosarcoma we detected a mutation cgg→tgg (arginine→tryptophan) in codon no. 282. © 1993 Baillière Tindall.

引用

页码：387 / 390

页数：4

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