PSORIASIS INDUCED BY INTERFERON-ALPHA

被引：143
|
作者：
FUNK, J [1 ]
LANGELAND, T [1 ]
SCHRUMPF, E [1 ]
HANSSEN, LE [1 ]
机构：
[1] NATL HOSP NORWAY,DEPT INTERNAL MED,OSLO 1,NORWAY
来源：
BRITISH JOURNAL OF DERMATOLOGY | 1991年 / 125卷 / 05期
关键词：
D O I：
10.1111/j.1365-2133.1991.tb14774.x
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Recombinant human interferon-alpha has been used in the treatment of several cancers, but there have been several reports that it may exacerbate psoriasis or trigger off its onset. We report four patients, three of whom first developed psoriasis and one who had an aggravation of the condition during treatment with interferon-alpha. Three of the patients had the carcinoid syndrome and one a renal carcinoma, and all were treated with interferon-alpha-2b or 2a (IFN-alpha-2b, 2a) with doses ranging from 1.5 x 1O(6) U daily to 18 x 10(6) U three times weekly. In two of the patients there appeared to be a correlation between the severity of the psoriasis and the dosage of interferon.
引用
收藏
页码：463 / 465
页数：3
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