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MENINGOCOCCAL INFECTION - EVIDENCE FOR SCHOOL TRANSMISSION
被引:7
|作者:
WALL, R
WILSON, J
MACARDLE, B
VELLANI, Z
机构:
[1] NORTHWICK PK HOSP & CLIN RES CTR,DEPT PAEDIAT,HARROW HA1 3UJ,MIDDX,ENGLAND
[2] NORTHWICK PK HOSP & CLIN RES CTR,DEPT COMMUNITY MED,HARROW HA1 3UJ,MIDDX,ENGLAND
关键词:
D O I:
10.1016/0163-4453(91)92074-F
中图分类号:
R51 [传染病];
学科分类号:
100401 ;
摘要:
Intimate contacts of a patient with meningococcal disease are at greater risk of disease than the general population and are offered chemoprophylaxis in order to prevent secondary cases. School contact is not considered a risk factor unless a further case develops. Bacteriological sampling of contacts to identify potential sources of infection is not considered warranted. We have questioned these approaches and investigated the contacts of a 9-year-old child with meningitis caused by sulphonamide-sensitive Neisseria meningitidis group C. Household carriers were not identified but 7/34 classmates were carrying the index strain suggesting that transmission was occurring within this population. The current recommendations for prophylaxis are based on information gathered in socioepidemiological settings, and involving strains which differ from those now prevalent. Such extrapolations may not be justified and further microbiological studies seem warranted to re-examine meningococcal transmission and prophylaxis usage in school children. © 1991 The British Society for the Study of Infection.
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页码:155 / 159
页数:5
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