Synthesis of New Benzofuran Derivatives and Evaluation of their Antimicrobial Activities

被引：0
|
作者：
El-Serwy, Weam S. [1 ]
Mohamed, Neama A. [2 ]
El-Serwy, Walaa S. [2 ]
Kassem, Emad M. M. [2 ]
Abd El Aty, Abeer A. [1 ]
机构：
[1] Natl Res Ctr, Dept Chem Nat & Microbial Prod, Div Pharmaceut Ind, Giza, Egypt
[2] Natl Res Ctr, Therapeut Chem Dept, Giza, Egypt
来源：
RESEARCH JOURNAL OF PHARMACEUTICAL BIOLOGICAL AND CHEMICAL SCIENCES | 2015年 / 6卷 / 03期
关键词：
Benzofuran; Nicotinonitrile; Antibacterial; Antimicrobial;
D O I：
暂无
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Starting from 6-(2,6-dibromo-4,7-dimethoxybenzofuran-5-yl)-2-hydrazinyl-4-(4-methoxyphenyl) nicotinonitrile 5, novel heterocyclic derivatives of benzofuran were synthesized 6-18. Biological evaluation in vitro revealed that compounds 15, 6, 10 and 18 exhibited a wide range of antibacterial activity against gram positive and gram negative bacteria.
引用
收藏
页码：213 / 224
页数：12
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