SYNTHESIS OF PARA-TRIFLUOROACETAMIDOPHENYLETHYL O-(2-ACETAMIDO-2-DEOXY-BETA-D-GALACTOPYRANOSYL)-(1-]4)-O-BETA-D-GALACTOPYRANOSYL-(1-]4)-O-BETA-D-GLUCOPYRANODISE, CONTAINING THE TRISACCHARIDE PORTION OF THE ASIALO-GM2 GLYCOLIPID

被引：9

作者：

KALLIN, E

LONN, H

NORBERG, T

机构：

[1] Organic Synthesis Department, Lund, S-223 70, BioCarb AB

来源：

JOURNAL OF CARBOHYDRATE CHEMISTRY | 1990年 / 9卷 / 05期

关键词：

D O I：

10.1080/07328309008543866

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The p-trifluoroacetamidophenylethyl β-glycoside 9 of the trisaccharide 0-(2-acetamido-2-deoxy-β-D-galactopyranosyl)-(l—4)-0-P*D-galactopyranosyl-(l-»4)-D-glucopyranose (gangliotriose, asialo-GM2) was synthesised. The key step was coupling of a suitably protected lactose derivative with a galactosamine thioglycoside derivative using sulfuryl chloride/trifluoromethanesulfonic acid activation. © 1990, Taylor & Francis Group, LLC. All rights reserved.

引用

页码：721 / 733

页数：13

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