FACILE SYNTHESIS OF 5-SUBSTITUTED 2-ACETYLTHIOPHENES

被引：0
|
作者：
GODA, H [1 ]
SATO, M [1 ]
IHARA, H [1 ]
HIRAYAMA, C [1 ]
机构：
[1] SUMITOMO SEIKA CHEM CO LTD,RES LAB I,HYOGO 67501,JAPAN
来源：
SYNTHESIS-STUTTGART | 1992年 / 09期
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D O I：
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中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
5-Substituted 2-(alpha-alkoxyimino)ethylthiophenes 4-8 are obtained by the reaction of 2-(alpha-alkoxyimino)ethylthiophenes 3 and electrophilic reagents. Hydrolysis of thiophenes 4-8 produces 5-substituted 2-acetylthiophenes 9-13, respectively. Compounds 3 are easily obtained either by the reaction of 2-acetylthiophene (1) and an O-alkylhydroxylamine or by oxidation of 1 followed by O-alkylation.
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页码：849 / 851
页数：3
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