Aim: The aim of this review is to update the knowledge about the Kawasaki disease (KD) which includes the way of early detection and latest treatment plan for the disease. Method: A number of literatures were reviewed and latest information about the etiology, diagnosis, laboratory investigation, treatment and outcome of the disease was collected and depicted in the review article. Result: Kawasaki disease is a multisystem vasculitis mainly affecting medium sized blood vessels. It is the second most common cause of vasculitis after Henoch Scholein Purpura (HSP) in children. Etiology of the disease is still unknown. Auto-immunity with genetic influence is thought to associate with the disease. Many physicians are ignorant of the disease. The pediatrician must be aware of the disease and suspect this condition in less than 5 year old children presenting with more than 5 days fever. the number of methods on the basis of criteria is set for the diagnosis of the disease. Latest treatment plan is set up for the disease which reduces the morbidity and mortality to a great extent. Conclusion: Physicians must have consciousness and comprehensive knowledge for the early suspicion of this disease. Any child presenting with fever for more than 5 days should not be ignored and other criteria of KD have to be evaluated by the physician. Early diagnosis and updated treatment are imperative for the prevention of morbidity and mortality for the disease.
机构:
Post Grad Inst Med Educ & Res PGIMER, Dept Pediat, Allergy Immunol Unit, Adv Pediat Ctr, Chandigarh 160012, IndiaPost Grad Inst Med Educ & Res PGIMER, Dept Pediat, Allergy Immunol Unit, Adv Pediat Ctr, Chandigarh 160012, India
Pilania, Rakesh Kumar
Jindal, Ankur Kumar
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Post Grad Inst Med Educ & Res PGIMER, Dept Pediat, Allergy Immunol Unit, Adv Pediat Ctr, Chandigarh 160012, IndiaPost Grad Inst Med Educ & Res PGIMER, Dept Pediat, Allergy Immunol Unit, Adv Pediat Ctr, Chandigarh 160012, India
Jindal, Ankur Kumar
Guleria, Sandesh
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Post Grad Inst Med Educ & Res PGIMER, Dept Pediat, Allergy Immunol Unit, Adv Pediat Ctr, Chandigarh 160012, IndiaPost Grad Inst Med Educ & Res PGIMER, Dept Pediat, Allergy Immunol Unit, Adv Pediat Ctr, Chandigarh 160012, India
Guleria, Sandesh
Singh, Surjit
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Post Grad Inst Med Educ & Res PGIMER, Dept Pediat, Allergy Immunol Unit, Adv Pediat Ctr, Chandigarh 160012, IndiaPost Grad Inst Med Educ & Res PGIMER, Dept Pediat, Allergy Immunol Unit, Adv Pediat Ctr, Chandigarh 160012, India
机构:
Royal Childrens Hosp, Dept Gen Med, Infect Dis Unit, Melbourne, Australia
Murdoch Childrens Res Inst, Infect Immun & Global Hlth, Melbourne, AustraliaRoyal Childrens Hosp, Dept Gen Med, Infect Dis Unit, Melbourne, Australia
Tsoi, Shu Ki
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机构:
Burgner, David
Ulloa-Gutierrez, Rolando
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Hosp Nacl Ninos Dr Carlos Saenz Herrera, Serv Infectol, Caja Costarricense Seguro Social CCSS, San Jose, Costa Rica
Univ Ciencias Med UCIMED, San Jose, Costa Rica
Inst Invest Ciencias Med IICIMED, San Jose, Costa Rica
Acad Nacl Med Costa Rica ACANAMED, San Jose, Costa RicaRoyal Childrens Hosp, Dept Gen Med, Infect Dis Unit, Melbourne, Australia
Ulloa-Gutierrez, Rolando
Phuong, Linny K.
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Royal Childrens Hosp, Dept Gen Med, Infect Dis Unit, Melbourne, Australia
Univ Melbourne, Dept Paediat, Melbourne, Australia
Murdoch Childrens Res Inst, Antimicrobials Theme Grp, Melbourne, AustraliaRoyal Childrens Hosp, Dept Gen Med, Infect Dis Unit, Melbourne, Australia
机构:
Department of Medicine, Rheumatology Program, Children’s Hospital, Boston, MA 02115
Department of Pediatrics, Harvard Medical School, Boston, MA 02115Department of Medicine, Rheumatology Program, Children’s Hospital, Boston, MA 02115
机构:
Division of Pediatric Cardiology, St. Louis Univ. School of Medicine, St. Louis, MO
Division of Pediatric Cardiology, Cardinal Glennon Children's Hospital, St. Louis, MO 63104Division of Pediatric Cardiology, St. Louis Univ. School of Medicine, St. Louis, MO
机构:
Louisiana State Univ, New Orleans, LA 70112 USALouisiana State Univ, New Orleans, LA 70112 USA
Rife, Eileen
Gedalia, Abraham
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Childrens Hosp, Div Pediat Rheumatol, 2000 Henry Clay Ave, New Orleans, LA 70118 USA
LSU Hlth Sci Ctr, 2000 Henry Clay Ave, New Orleans, LA 70118 USALouisiana State Univ, New Orleans, LA 70112 USA