Susceptibility of Glycopeptide-Resistant Enterococci to Linezolid, Quinupristin/dalfopristin, Tigecycline and Daptomycin in a Tertiary Greek Hospital

被引：4
|
作者：
Maraki, Sofia [1 ]
Samonis, George [2 ]
Dimopoulou, Dimitra [2 ]
Mantadakis, Elpis [3 ,4 ]
机构：
[1] Univ Hosp Heraklion, Dept Clin Microbiol Parasitol Zoonoses & Geog Med, Iraklion, Greece
[2] Univ Crete, Sch Med, Dept Internal Med, Infect Dis Unit, Iraklion, Greece
[3] Democritus Univ Thrace, Fac Med, Dept Pediat, Komotini, Greece
[4] Univ Gen Dist Hosp Alexandroupolis, Thrace, Greece
来源：
INFECTION AND CHEMOTHERAPY | 2014年 / 46卷 / 04期
关键词：
Daptomycin; Glycopeptide-resistant enterococci; Linezolid; Quinupristin/dalfopristin; Teicoplanin; Tigecycline;
D O I：
10.3947/ic.2014.46.4.253
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
We investigated the antibiotic susceptibility of glycopeptide-resistant enterococci (GRE). Seventy consecutive GRE were tested. Sixty-two isolates were identified as Enterococcus faecium (88.6%), and 8 (11.4%) as Enterococcus faecalis. All strains were susceptible to linezolid and daptomycin, while 17.1% (12/70) and 11.4% (8/70) were resistant to quinupristin/dalfopristin (QD) and tigecycline, respectively. All E. faecalis isolates were resistant to QD, while 4 of 62 (6.5%) E. faecium isolates were resistant to QD. All E. faecalis isolates were susceptible to tigecycline, while 14.5% (9/62) E. faecium isolates were resistant. Continued surveillance of GRE antibiotic susceptibilities is important for combating these multi-resistant nosocomial pathogens.
引用
收藏
页码：253 / 256
页数：4
相关论文
共 38 条
  • [1] In vitro activities of tigecycline, daptomycin, linezolid and quinupristin/dalfopristin against glycopeptide-resistant Enterococcus faecium
    Abb, Jochen
    [J]. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2007, 29 (03) : 358 - 360
  • [2] Susceptibility of glycopeptide-resistant Enterococcus faecium to tigecycline, dapto-mycin, linezolid, and quinupristin-dalfopristin
    Abb, J.
    [J]. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2007, 29 : S615 - S615
  • [3] Investigation of Linezolid, Daptomycin, Quinupristin-Dalfopristin and Tigecycline Susceptibilities against Vancomycin Resistant Enterococcus Isolates
    Yasemin, C. A. G.
    Serap, Gencer
    Oznur, A. K.
    Yakup, C. A. G.
    Serdar, Ozer
    [J]. JOURNAL OF PURE AND APPLIED MICROBIOLOGY, 2013, 7 (02): : 1367 - 1371
  • [4] Linezolid is active in vitro against quinupristin/dalfopristin resistant enterococci and staphylococci
    Siddiqui, F
    Peterson, LR
    Noskin, GA
    [J]. CLINICAL INFECTIOUS DISEASES, 2001, 33 (07) : 1179 - 1179
  • [5] Antimicrobial activity of mupirocin, daptomycin, linezolid, quinupristin/dalfopristin and tigecycline against vancomycin-resistant enterococci (VRE) from clinical isolates in Korea (1998 and 2005)
    Lee, Do Kyung
    Kim, Yuna
    Park, Kun Sup
    Yang, Jae Wook
    Kim, Kyungjae
    Ha, Nam Joo
    [J]. JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2007, 40 (06): : 881 - 887
  • [6] IN-VITRO ANTIMICROBIAL SUSCEPTIBILITY OF GLYCOPEPTIDE-RESISTANT ENTEROCOCCI
    FREEMAN, C
    ROBINSON, A
    COOPER, B
    MAZENSSULLIVAN, M
    QUINTILIANI, R
    NIGHTINGALE, C
    [J]. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 1995, 21 (01) : 47 - 50
  • [7] Characterization of glycopeptide-resistant enterococci from a Swiss hospital
    Liassine, N
    Frei, R
    Jan, I
    Auckenthaler, R
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 1998, 36 (07) : 1853 - 1858
  • [8] In vitro activities of daptomycin, vancomycin, linezolid, and quinupristin-dalfopristin against staphylococci and enterococci, including vancomycin-intermediate and -resistant strains
    Rybak, MJ
    Hershberger, E
    Moldovan, T
    Grucz, RG
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (04) : 1062 - 1066
  • [9] TREATMENT OF CAPD-PERITONITIS DUE TO GLYCOPEPTIDE-RESISTANT ENTEROCOCCUS-FAECIUM WITH QUINUPRISTIN DALFOPRISTIN
    LYNN, WA
    CLUTTERBUCK, E
    WANT, S
    MARKIDES, V
    LACEY, S
    ROGERS, TR
    COHEN, J
    [J]. LANCET, 1994, 344 (8928): : 1025 - 1026
  • [10] Association between quinupristin/dalfopristin resistance in glycopeptide-resistant Enterococcus faecium and the use of additives in animal feed
    Werner, G
    Klare, I
    Witte, W
    [J]. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 1998, 17 (06) : 401 - 402
1234