Our paper analyses a series of epigrams from the Greek Anthology, namely those who directly concern the character of Medea. By adding the available data on the main plastic representations that also portrait Medea, we trace a sketch for the development of the interpretations on the aforementioned woman in Roman imperial times, from a more complex image of both the sorrow mother and the betrayed woman, to the complete banishment of any trace of humanity, when the Colchidian becomes the model of an unbearable and savage murderer.