FUNCTION OF SNRNPS IN PRE-MESSENGER-RNA SPLICING

被引：3
|
作者：
LYGEROU, Z [1 ]
KANDELSLEWIS, S [1 ]
SERAPHIN, B [1 ]
机构：
[1] EMBL,DEPT CELLULAR BIOL,GENE EXPRESS PROGRAM,MEYERHOFSTR 1,POSTFACH 102209,W-6900 HEIDELBERG,GERMANY
来源：
M S-MEDECINE SCIENCES | 1993年 / 9卷 / 02期
关键词：
D O I：
10.4267/10608/2889
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Splicing of intron sequence is a pre-mRNA processing step that occurs in the cell nucleus. snRNPs (small nuclear RiboNucleoProteins) are splicing factors made of one or more RNAs associated with proteins. It is now clear that snRNPs are required for intron recognition and splice site selection. The assembly pathway of snRNPs on the pre-mRNA is ordered and results in the formation of a splicing complex or spliceosome. Inside the spliceosome, snRNAs could catalyze the splicing reaction.
引用
收藏
页码：165 / 170
页数：6
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