GENETIC APPROACHES TO NUCLEAR-PORE STRUCTURE AND FUNCTION

被引：82
|
作者：
DOYE, V [1 ]
HURT, EC [1 ]
机构：
[1] EUROPEAN MOLEC BIOL LAB,D-69117 HEIDELBERG,GERMANY
来源：
TRENDS IN GENETICS | 1995年 / 11卷 / 06期
关键词：
D O I：
10.1016/S0168-9525(00)89057-5
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The major features of nucleocytoplasmic transport through nuclear pore complexes are conserved from yeast to humans. This transport machinery, which includes the 125 MDa nuclear pore complex structure, has been molecularly dissected in the yeast Saccharomyces cerevisiae by genetic approaches. Here, we summarize the genetic analyses used to elucidate structure-function relationships within this large supramolecular assembly.
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收藏
页码：235 / 241
页数：7
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