RESPONSE TO DESIPRAMINE TREATMENT IN ADOLESCENT MAJOR DEPRESSION

被引：0

作者：

BOULOS, C ^{[1
]}

KUTCHER, S ^{[1
]}

MARTON, P ^{[1
]}

SIMEON, J ^{[1
]}

FERGUSON, B ^{[1
]}

ROBERTS, N ^{[1
]}

机构：

[1] UNIV OTTAWA,ROYAL OTTAWA HOSP,OTTAWA K1N 6N5,ONTARIO,CANADA

来源：

PSYCHOPHARMACOLOGY BULLETIN | 1991年 / 27卷 / 01期

关键词：

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Thirty adolescents (ages 15-20) who met DSM-III-R criteria for major depressive disorder completed a double-blind, placebo-controlled, 6-week, fixed-dose (200 mg daily) study of desipramine (DMI). Thirty-three percent of the placebo group and 50 percent of the DMI group improved (greater-than-or-equal-to 50% change on the Hamilton Rating Scale for Depression). Subjective reports of adverse effects did not significantly differentiate the two groups. Major adverse effects, necessitating study discontinuation, occurred solely in the DMI group.

引用

页码：59 / 65

页数：7

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