MODERN APPROACHES TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH CONCOMITANT CHRONIC HEART FAILURE

The foreign and domestic literature and the results of different studies are summarized in the review artricle, to consider the possibility of pharmacotherapy and synthesis of existing information about the treatment of patients with COPD and concomitant cardiac insufficiency. There are a lot of different studies which are already published demonstrating the existence of a direct association between COPD and cardiovascular clinical outcomes. The treatment strategy in patients with COPD and concomitant cardiac insufficiency should be aware of the risk of the total prescribed drug groups. Some drugs are traditionally prescribed in patients with CCI (ACE inhibitors, beta-blockers, statins) have a negative effect on the course of COPD, and glukocorticosteroids, without which it is difficult to cure COPD, may have adverse effects on the cardiovascular system. The difficulties of drug therapy are in mutually exclusive approaches to the treatment of COPD and concomitant cardiovascular disease. The concept of co-treatment of respiratory and cardiovascular disease supplemented and extended these last few years. The discovery of new mechanisms of action have already known drugs, revised ratio of "risk-benefit" in their nomination in this group of patients. But despite that management of these patients remains a challenge for physicians and requires a well-considered assignments. The goal of treatment is control over the prevention of disease progression, mortality reduction, increased exercise tolerance, improving the quality of life of the patient.