Recent clinical trials in diabetes - implications for managing older patients

被引：0
|
作者：
Hawthorne, G. C. [1 ]
Yarnall, A. J. [2 ]
机构：
[1] Newcastle Gen Hosp, Diabetes Ctr, Newcastle Upon Tyne, Tyne & Wear, England
[2] Freeman Rd Hosp, Dept Care Elderly, Newcastle Upon Tyne, Tyne & Wear, England
来源：
REVIEWS IN CLINICAL GERONTOLOGY | 2009年 / 19卷 / 01期
关键词：
Diabetes mellitus; elderly; glycaemic targets; microvascular disease; macrovascular disease; ypoglycaemia; cognitive function;
D O I：
10.1017/S0959259809990104
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
The prevalence of type 2 diabetes is set to increase, and with it the complications associated with diabetes. Since 2007 there have been a number of significant trials that may change the way we think about treating people with diabetes, especially our older patients. These trials include the Steno-2 trial, UKPDS legacy trial, ADVANCE, ACCORD and VADT. These trials are reviewed in detail in this article, including the implications for the patients we treat. Recent work assessing the effect of HbA1c on cognitive function and the effects of hypoglycaemia are also discussed. We conclude with suggestions for targets for glycated haemoglobin level based on NICE guidance.
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页码：25 / 33
页数：9
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