AN ETHICAL AND LEGAL OVERVIEW OF PHARMACOGENOMICS: PERSPECTIVES AND ISSUES

被引：0

作者：

Srnon, Guillaume ^{[1
]}

Joly, Yann ^{[1
]}

Feldman, Sabrina ^{[1
]}

Avard, Denise ^{[1
]}

机构：

[1] Univ Montreal, Ctr Rech Droit Publ, Montreal, PQ, Canada

来源：

MEDICINE AND LAW | 2008年 / 27卷 / 04期

关键词：

Pharmacogenomics; research; ethics; professional responsibilities; health professionals; clinical trials;

D O I：

暂无

中图分类号：

D9 [法律]; DF [法律];

学科分类号：

0301 ;

摘要：

Pharmacogenomics, a field of study at the interface of the disciplines of genomics and pharmacology, strives to understand the interaction between genes and the response to therapeutics. Its introduction into clinical research trials and medical practice promises to optimize the effectiveness of medications, reduce the adverse effects experienced by patients, and improve the research and development of new therapeutics. However, while pharmacogenomics promises tremendous health benefits it is still crucial to critically analyze the ethical, social and legal issues surrounding these developments. First, we present the numerous potential benefits of pharmacogenomics. Then, using a thorough review of relevant jurisprudence, policies and literature, the main ethical, social and legal issues associated with pharmacogenomics will be identified. The likely new responsibilities for health care professionals and pharmaceutical companies as a result of pharmacogenomic development will also be discussed.

引用

页码：843 / 857

页数：15

共 50 条

[1] Ethical, social and legal issues in pharmacogenomics
Wertz, DC
[J]. PHARMACOGENOMICS JOURNAL, 2003, 3 (04): : 194 - 196
[2] Ethical, social and legal issues in pharmacogenomics
D C Wertz
[J]. The Pharmacogenomics Journal, 2003, 3 : 194 - 196
[3] Legal and ethical issues for pharmacogenomics: the Ubiquitous Pharmacogenomics state of the art
Constantin, A.
Dupui, M.
Rial-Sebbag, E.
[J]. EUROPEAN JOURNAL OF HUMAN GENETICS, 2018, 26 : 812 - 812
[4] The Ethical, Legal and Regulatory Issues Associated with Pharmacogenomics: Systematically Quantifying the Literature
Hewitt, Jayne E.
[J]. JOURNAL OF LAW AND MEDICINE, 2018, 25 (03) : 782 - 793
[5] Ethical and legal implications of pharmacogenomics
Rothstein, MA
Epps, PG
[J]. NATURE REVIEWS GENETICS, 2001, 2 (03) : 228 - 231
[6] Ethical and legal implications of pharmacogenomics
Mark A. Rothstein
Phyllis Griffin Epps
[J]. Nature Reviews Genetics, 2001, 2 : 228 - 231
[7] Ethical and Social Issues in Pharmacogenomics Testing
Vijverberg, S. J. H.
Pieters, T.
Cornel, M. C.
[J]. CURRENT PHARMACEUTICAL DESIGN, 2010, 16 (02) : 245 - 252
[8] LEGAL AND PHILOSOPHICAL-PERSPECTIVES ON ETHICAL ISSUES - THEOLOGIANS VIEW
SHRIVER, DW
[J]. BULLETIN OF THE NEW YORK ACADEMY OF MEDICINE, 1978, 54 (08) : 797 - 807
[9] Human resource information systems: An overview of current ethical and legal issues
Hubbard, JC
Forcht, KA
Thomas, DS
[J]. JOURNAL OF BUSINESS ETHICS, 1998, 17 (12) : 1319 - 1323
[10] LEGAL AND ETHICAL ISSUES
ALLAN, RE
[J]. AMERICAN INDUSTRIAL HYGIENE ASSOCIATION JOURNAL, 1991, 52 (03): : A158 - A159

← 1 2 3 4 5 →