Curacins B and C, new antimitotic natural products from the marine cyanobacterium Lyngbya majuscula

被引：49
|
作者：
Yoo, HD [1 ]
Gerwick, WH [1 ]
机构：
[1] OREGON STATE UNIV,COLL PHARM,CORVALLIS,OR 97331
来源：
JOURNAL OF NATURAL PRODUCTS | 1995年 / 58卷 / 12期
关键词：
D O I：
10.1021/np50126a029
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new and potent antimitotic metabolites, curacins B [2] and C [3], were isolated from a Curacao collect ion of Lyngbya majuscula. The structures of 2 and 3, geometrical isomers of the known compound curacin A [1], were determined by derailed spectroscopic analysis in comparison with 1. The absolute stereochemical configuration of 2 was deduced ro be 2R,13R,19R,21S by ics thermally induced interconversion with 1.
引用
收藏
页码：1961 / 1965
页数：5
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