Value of F-18 NaF PET/CT in the Detection and Global Quantification of Cardiovascular Molecular Calcification as Part of the Atherosclerotic Process

被引:0
|
作者
Basu, Sandip [1 ]
Beheshti, Mohsen [2 ]
Alavi, Abass [3 ]
机构
[1] Bhabha Atom Res Ctr, Radiat Med Ctr, Bombay 400012, Maharashtra, India
[2] St Vincents Hosp, PET CT Ctr LINZ, Dept Nucl Med & Endocrinol, A-4010 Linz, Austria
[3] Univ Penn, Sch Med, Hosp Univ Penn, Div Nucl Med, 3400 Spruce St, Philadelphia, PA 19104 USA
关键词
F-18 NaF PET; Computed tomography; Cardiovascular molecular calcification; Atherosclerosis;
D O I
10.1016/j.cpet.2012.04.006
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Detection of early ongoing cardiovascular molecular calcification and its quantification through F-18-labeled sodium fluoride (F-18 NaF) PET/computed tomography (CT) imaging has been a recent addition to the diagnostic armamentarium of molecular imaging for the atherosclerotic process. At present, visual detection of molecular calcification as well as its regional quantification on (F-18 NaF) PET/CT are suboptimal, mainly because of the very low degree of uptake of this radiotracer in the heart and major vessels, and hence subject to the partial volume effect. Calculation of cardiovascular F-18 NaF uptake in the heart and arterial wall using automated software is an innovative approach.
引用
收藏
页码:329 / +
页数:12
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