Reduction in the biomechanical competence of the axial skeleton can result in challenging complications. Reduction of bone mass and osteoporotic fractures creates specific challenges that cannot be met with pharmacotherapy alone. Physical rehabilitative measures play a key role after fracture and beyond for preventing further fracture. Muscle reeducation, resistance exercises for strengthening, and reduction of kyphosis are key elements for reducing the risk of falls and further fracture. Global programs for prevention and management of osteoporotic fractures should include physical rehabilitation measures. When needed, the Spinal Proprioceptive Extension Exercise Dynamic (SPEED) Program needs to be implemented.