Linear Epidermal Nevus with Epidermolytic Hyperkeratosis Case description

Introduction: Epidermal nevus is an anomaly of epidermal development that can affect any part of the body, although usually reported in the extremities. Although it is not uncommon, the presence of epidermolytic hyperkeratosis on skin biopsy is a relatively uncommon finding in the literature. Case report: We report the case of a 2-year old male diagnosed with unilateral linear verrucous epidermal nevus of the left hemisphere with histopathological evidence of epidermolytic hyperkeratosis. Comments: Unilateral linear epidermal nevi are a rare form of epidermal nevus, and are also unusual in the presence of epidermolytic hyperkeratosis. They usually occur within the first 5 years of life and the lesions are intensely itchy. These nevi are often refractory to topical therapy and surgical removal may be an option to improve symptoms