LOCATION AND CHARACTERIZATION OF THE BOVINE HERPESVIRUS TYPE 4 THYMIDINE KINASE GENE - COMPARISON WITH THYMIDINE KINASE GENES OF OTHER HERPESVIRUSES

被引：28

作者：

LOMONTE, P

BUBLOT, M

PASTORET, PP

THIRY, E

机构：

[1] Virology Department, Faculty of Veterinary Medicine, University of Liège, Liège

来源：

ARCHIVES OF VIROLOGY | 1992年 / 127卷 / 1-4期

关键词：

D O I：

10.1007/BF01309595

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The location and nucleotide sequence of the bovine herpesvirus type 4 (BHV-4) thymidine kinase (TK) gene was determined. The coding region of the TK gene is 1335 nucleotides long and corresponds to a polypeptide of 445 amino acids. Comparison of TK amino acid sequences of BHV-4 and 16 herpesvirus TKs reveals a greater homology to those of the gammaherpesviruses EBV and specially HVS, than to those of alphaherpesviruses. The open reading frames detected in the vicinity of TK gene were homologous to the corresponding ones in other herpesviruses.

引用

页码：327 / 337

页数：11

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