Evaluation of antibacterial activity of Achyranthes aspera extract against Streptococcus mutans: An in vitro study

被引:17
|
作者
Yadav, Roma [1 ]
Rai, Radhika [2 ]
Yadav, Abhishek [1 ]
Pahuja, Meetika [4 ]
Solanki, Savita [3 ]
Yadav, Himani [1 ]
机构
[1] NIMS Dent Coll, Dept Publ Hlth Dent, Jaipur, Rajasthan, India
[2] SGT Univ, Fac Dent Sci, Dept Oral & Maxillofacial Pathol, Gurgaon, India
[3] PDM Dent Coll, Dept Publ Hlth Dent, Bahadurgarh, Haryana, India
[4] Subharti Dent Coll, Dept Publ Hlth Dent, Meerut, Uttar Pradesh, India
关键词
Achyranthes aspera; antibacterial activity; apamarga; chlorhexidine; Streptococcus mutans;
D O I
10.4103/2231-4040.191426
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Dental caries and periodontal diseases have historically been considered the most important global oral health burdens. Many chemicals and synthetic drugs have marked the side effects. Hence, there has been a paradigm shift from the use of modern drugs to the age-old herbs. Achyranthes aspera is one such important plant with various established pharmaceutical properties. The aim of this study was to assess the antibacterial activity of the A. aspera extract against Streptococcus mutans. Aqueous extract of A. aspera was prepared. Different concentrations of the root and stem extracts of A. aspera were transferred to the agar plates, which had been streaked with the bacterium S. mutans. The plates were incubated aerobically at 37 degrees C for 24 h, and the zones of inhibition were measured using cup plate method. A. aspera extract showed statistically significant zones of inhibition. A. aspera showed marked antibacterial activity against S. mutans.
引用
收藏
页码:149 / 152
页数:4
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