A STUDY ON EARLY ONSET CORONARY ARTERY DISEASE IN RELATION TO HYPER HOMOCYSTEINEMIA IN PATIENTS YOUNGER THAN 40 YEARS OF AGE

There has been a rising incidence of myocardial infarction as a whole in recent times much because of changing pattern of life style, urbanization, changing food habits, and increase in cigarette smoking, psycho social stress and increase in the incidence of diabetes mellitus. Adding to this there is drastic increase in the incidence of MI in young people much to the influence of novel risk factors which are of current debate especially homocysteine, lipoprotein little (a), fibrinogen, anticardiolipin antibody, protein C, protein S and antithrombin deficiency. The first ever positive prospective study on plasma homocystein and CAD was reported in 1992 by Selhubetal who showed an association of plasma homocysteine with extracranial carotid stenosis in the elderly. We report our study to analyze the special risk factors of MI in patients younger than 40years of age in special reference to serum homocysteine levels.