CYTOSKELETAL COMPOSITION OF ATTACHING AND EFFACING LESIONS ASSOCIATED WITH ENTEROPATHOGENIC ESCHERICHIA-COLI ADHERENCE TO HELA-CELLS

被引：188
|
作者：
FINLAY, BB
ROSENSHINE, I
DONNENBERG, MS
KAPER, JB
机构：
[1] UNIV BRITISH COLUMBIA, DEPT BIOCHEM, VANCOUVER V6T 1W5, BC, CANADA
[2] UNIV BRITISH COLUMBIA, DEPT MICROBIOL, VANCOUVER V6T 1W5, BC, CANADA
[3] UNIV MARYLAND, SCH MED, CTR VACCINE DEV, DEPT MED, BALTIMORE, MD 21201 USA
来源：
INFECTION AND IMMUNITY | 1992年 / 60卷 / 06期
关键词：
D O I：
10.1128/IAI.60.6.2541-2543.1992
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The cytoskeletal lesions associated with enteropathogenic Escherichia coli adhering to cultured HeLa epithelial cells were examined by immunofluorescence microscopy. The microfilament-associated proteins actin, alpha-actinin, talin, and ezrin were localized with adherent enteropathogenic E. coli, whereas tropomyosin, keratin and vimentin (intermediate filaments), tubulin (microtubules), and vinculin were not localized. These cytoskeletal structures differed significantly from those associated with Salmonella typhimurium internalization (invasion).
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页码：2541 / 2543
页数：3
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