THE EFFICIENT AND UNBIASED ESTIMATION OF NUCLEAR SIZE VARIABILITY USING THE SELECTOR

被引:9
|
作者
MCMILLAN, AM
SORENSEN, FB
机构
[1] UNIV LIVERPOOL,DEPT HUMAN ANAT & CELL BIOL,QUANTIT 3D MICROSCOPY GRP,POB 147,LIVERPOOL L69 3BX,ENGLAND
[2] AARHUS UNIV,INST PATHOL,STEREOL RES LAB,DK-8000 AARHUS,DENMARK
[3] AARHUS UNIV,INST EXPTL CLIN RES,INTERNAL MED 2 CLIN,DK-8000 AARHUS,DENMARK
来源
关键词
STEREOLOGY; OPTICAL DISECTOR; NUCLEAR VOLUME; MELANOCYTIC TUMOR;
D O I
10.1111/j.1365-2818.1992.tb01498.x
中图分类号
TH742 [显微镜];
学科分类号
摘要
The selector was used to make an unbiased estimation of nuclear size variability in one benign naevocellular skin tumour and one cutaneous malignant melanoma. The results showed that the estimates obtained using the selector were comparable to those obtained using the more time consuming Cavalieri-disector approach. Employing 'optical sections', the selector was found to be between five and ten times more efficient than the Cavalieri-disector method when using physical sections.
引用
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页码:433 / 437
页数:5
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