Genetic characterization of 52 autosomal SNPs in the Portuguese population

被引：4
|
作者：
Pereira, R. e [1 ,2 ]
Fondevila, M. [2 ]
Phillips, C. [2 ]
Amorim, A. [1 ,3 ]
Carracedo, A. [2 ]
Gusmao, L. [1 ]
机构：
[1] Univ Porto, IPATIMUP, Inst Mol Pathol & Immunol, Oporto, Portugal
[2] Univ Santiago de Compostela, Inst Legal Med, Santiago De Compostela, Spain
[3] Univ Porto, Fac Sci, Oporto, Portugal
来源：
FORENSIC SCIENCE INTERNATIONAL GENETICS SUPPLEMENT SERIES | 2008年 / 1卷 / 01期
关键词：
Population data; Single nucleotide polymorphism (SNP); Portugal;
D O I：
10.1016/j.fsigss.2007.10.160
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
For the Portuguese population no data were previously available for autosomal SNP genetic diversity and population structure. In this work we characterized 52 autosomal SNPs in the three regions from continental Portugal (North, Centre and South) using the SNPforID multiplex assay. Comparisons made between the three regions revealed genetic homogeneity of the studied SNPs throughout the country, allowing the use of a common database. Allele frequencies are presented for all markers as well as observed heterozygosity, discrimination power and genetic distances (FST) between regions. No significant deviations from Hardy-Weinberg equilibrium were detected. The high power of discrimination obtained in the Portuguese population confirms the utility of the 52-plex in identification studies. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：358 / 360
页数：3
相关论文
共 50 条
  • [1] Population data of 52 autosomal SNPs in Italian population
    Barbaro, A.
    Phillips, C.
    Fondevila, M.
    Carracedo, A.
    Lareu, M. V.
    [J]. FORENSIC SCIENCE INTERNATIONAL GENETICS SUPPLEMENT SERIES, 2009, 2 (01) : 351 - 352
  • [2] Genetic characterization of 52 autosomal SNPs in two sub-Saharan African populations
    Pereira, R.
    Fondevila, M.
    Phillips, C.
    Amorim, A.
    Carracedo, A.
    Gusmao, L.
    [J]. FORENSIC SCIENCE INTERNATIONAL GENETICS SUPPLEMENT SERIES, 2008, 1 (01) : 361 - 363
  • [3] Dual genetic structure of the Japanese population based on autosomal SNPs and haplotypes
    Yamaguchi, Yumi
    Tsunoda, Tatsuhiko
    Kumasaka, Natsuhiko
    Takahashi, Atsushi
    Hosono, Naoya
    Kubo, Michiaki
    Nakamura, Yusuke
    Kamatani, Naoyuki
    [J]. GENES & GENETIC SYSTEMS, 2011, 86 (06) : 441 - 441
  • [4] Genetic characterization of six SNPs in Catalonian population
    Barrot, C.
    Jimenez, S.
    Sanchez, C.
    Banon, E.
    Ortega, M.
    Huguet, E.
    Gene, M.
    [J]. FORENSIC SCIENCE INTERNATIONAL GENETICS SUPPLEMENT SERIES, 2011, 3 (01) : E317 - E318
  • [5] Genetic differences in the two main groups of the Japanese population based on autosomal SNPs and haplotypes
    Yamaguchi-Kabata, Yumi
    Tsunoda, Tatsuhiko
    Kumasaka, Natsuhiko
    Takahashi, Atsushi
    Hosono, Naoya
    Kubo, Michiaki
    Nakamura, Yusuke
    Kamatani, Naoyuki
    [J]. JOURNAL OF HUMAN GENETICS, 2012, 57 (05) : 326 - 334
  • [6] Genetic differences in the two main groups of the Japanese population based on autosomal SNPs and haplotypes
    Yumi Yamaguchi-Kabata
    Tatsuhiko Tsunoda
    Natsuhiko Kumasaka
    Atsushi Takahashi
    Naoya Hosono
    Michiaki Kubo
    Yusuke Nakamura
    Naoyuki Kamatani
    [J]. Journal of Human Genetics, 2012, 57 : 326 - 334
  • [7] Analysis of 49 autosomal SNPs in an Iraqi population
    Tomas, Carmen
    Diez, Isabel E.
    Moncada, Enrique
    Borsting, Claus
    Morling, Niels
    [J]. FORENSIC SCIENCE INTERNATIONAL-GENETICS, 2013, 7 (01) : 198 - 199
  • [8] Typing of 49 autosomal SNPs by SNaPshot® in the Slovenian population
    Drobnic, Katja
    Borsting, Claus
    Rockenbauer, Eszter
    Tomas, Carmen
    Morling, Niels
    [J]. FORENSIC SCIENCE INTERNATIONAL-GENETICS, 2010, 4 (05) : E125 - E127
  • [9] Characterization of HLA genetic polymorphism in a Portuguese population with ankylosing spondylitis
    Pimentel Santos, Fernando Manuel
    Ligeiro, Dario
    Mourao, Ana Filipa
    Bastos, Estela
    Chaves, Raquel
    Falcao, Sandra
    Guedes-Pinto, Henrique
    Trindade, Helder
    Branco, Jaime
    [J]. CELLULAR ONCOLOGY, 2007, 29 (02) : 155 - 155
  • [10] Characterization of HLA genetic polymorphism in a Portuguese population with ankylosing spondylitis
    Pimentel-Santos, F. M.
    Ligeiro, D.
    Matos, M.
    Mourao, F.
    Sousa, E.
    Riberiro, A.
    Sousa, M.
    Guedes-Pinto, H.
    Trindade, H.
    Branco, J. C.
    [J]. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2008, 26 (04) : 730 - 730
12345