ANTIFUNGAL ANTIBIOTIC FROM THE MUSHROOM AGROCYBE-AEGERITA (BRIG) SING

被引：14
|
作者：
STRANSKY, K [1 ]
SEMERDZIEVA, M [1 ]
OTMAR, M [1 ]
PROCHAZKA, Z [1 ]
BUDESINSKY, M [1 ]
UBIK, K [1 ]
KOHOUTOVA, J [1 ]
STREINZ, L [1 ]
机构：
[1] CZECHOSLOVAK ACAD SCI, INST MICROBIOL, CS-14220 PRAGUE 4, CZECHOSLOVAKIA
来源：
COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS | 1992年 / 57卷 / 03期
关键词：
D O I：
10.1135/cccc19920590
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An extract from a submersed culture of the mushroom Agrocybe aegerita (BRIG.) SING., containing antifungal antibiotic compounds was chromatographed on a silica gel column. Compounds from fractions which displayed the highest biological activity were concentrated and isolated by means of preparative thin-layer chromatography and preparative high-performance liquid chromatography, and were further characterized by means of gas chromatography, mass spectrometry and nuclear magnetic resonance. They are sesquiterpenic diols predominantly with an illudine skeleton. Structural formulae are proposed for some of them.
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页码：590 / 603
页数：14
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