EXPRESSION OF CGRP MESSENGER-RNAS IN THE PINK SALMON, ONCORHYNCHUS-GORBUSCHA

被引:11
|
作者
MAUBRAS, L
TABOULET, J
PIDOUX, E
LASMOLES, F
JULIENNE, A
MILHAUD, G
BENSON, AA
MOUKHTAR, MS
CRESSENT, M
机构
[1] CHU ST ANTOINE, INSERM, U113, 27 RUE CHALIGNY, F-75571 PARIS 12, FRANCE
[2] CHU ST ANTOINE, CNRS, UA 163, F-75571 PARIS 12, FRANCE
[3] UNIV CALIF SAN DIEGO, SCRIPPS INST OCEANOG, LA JOLLA, CA 92093 USA
关键词
PLASMA CGRP; CGRP RNAS; SALMON; REPRODUCTIVE CYCLE;
D O I
10.1016/0196-9781(93)90074-Q
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We report the isolation of calcitonin gene-related peptide (CGRP) mRNAs and expression of these RNAs in different tissues in the pink salmon, Oncorhynchus gorbuscha. Hybridization of poly(A+) RNAs indicated a mature CGRP RNA of 1.1 kb. The CGRP-like immunoreactivity occurring in tissues and plasma had the same relative molecular weight as the synthetic molecule. Variations in CGRP plasma levels were observed during migration. spawning, and postspawning states. These data suggest that CGRP may play an important role during the reproductive cycle of salmon.
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页码:977 / 981
页数:5
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