BETA-CARBOLINE ALKALOIDS .6. TOTAL SYNTHESIS OF THE PHOSPHODIESTERASE INHIBITOR INFRACTINE

被引：0

作者：

BRACHER, F ^{[1
]}

HILDEBRAND, D ^{[1
]}

机构：

[1] UNIV MARBURG,INST PHARMAZEUT CHEM,W-3550 MARBURG,GERMANY

来源：

PHARMAZIE | 1995年 / 50卷 / 03期

关键词：

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The alkaloid infractine was prepared by Heck-olefination of the triflate 4 with methyl acrylate followed by catalytic hydrogenation. Attempted alkinylation of 1-chloro-beta-carboline with ethyl propiolate resulted in exclusive 1,4-addition to the indole nitrogen.

引用

页码：182 / 183

页数：2

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