Budding of Enveloped Viruses: Interferon-Induced ISG15-Antivirus Mechanisms Targeting the Release Process

被引:15
|
作者
Seo, Eun Joo [1 ]
Leis, Jonathan [1 ]
机构
[1] Northwestern Univ, Feinberg Sch Med, Dept Microbiol & Immunol, Ward 4-065,303 E Chicago Ave, Chicago, IL 60611 USA
关键词
D O I
10.1155/2012/532723
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Pathogenic strains of viruses that infect humans are encapsulated in membranes derived from the host cell in which they infect. After replication, these viruses are released by a budding process that requires cell/viral membrane scission. As such, this represents a natural target for innate immunity mechanisms to interdict enveloped virus spread and recent advances in this field will be the subject of this paper.
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页数:10
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