Elderly patients often request treatment for cold and flu symptoms. Product selection may be more complicated in this patient group. The elderly are more at risk of adverse drug reactions due to an increased number of medical conditions and drugs taken, and also because of altered pharmacokinetics and pharmacodynamics, impaired renal function, reduced hepatic blood flow and liver size, increased body fat, decreased lean body mass, and changes in receptor sensitivity. This article will review the factors affecting pharmacology in the elderly, as well as the possible risks associated with some common products used in the treatment of colds and flu.
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Univ Limpopo, Fac Hlth Sci, Dept Pharm, Medunsa Campus, Polokwane, South AfricaUniv Limpopo, Fac Hlth Sci, Dept Pharm, Medunsa Campus, Polokwane, South Africa
Schellack, Natalie
Labuschagne, Quinten
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Univ Limpopo, Fac Hlth Sci, Dept Pharm, Medunsa Campus, Polokwane, South AfricaUniv Limpopo, Fac Hlth Sci, Dept Pharm, Medunsa Campus, Polokwane, South Africa
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Sefako Makgatho Hlth Sci Univ, Sch Pharm, Fac Hlth Sci, Ga Rankuwa, South AfricaSefako Makgatho Hlth Sci Univ, Sch Pharm, Fac Hlth Sci, Ga Rankuwa, South Africa
Dlamini, Z.
Kupa, K.
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Sefako Makgatho Hlth Sci Univ, Sch Pharm, Fac Hlth Sci, Ga Rankuwa, South AfricaSefako Makgatho Hlth Sci Univ, Sch Pharm, Fac Hlth Sci, Ga Rankuwa, South Africa
Kupa, K.
Schellack, N.
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Sefako Makgatho Hlth Sci Univ, Sch Pharm, Fac Hlth Sci, Ga Rankuwa, South AfricaSefako Makgatho Hlth Sci Univ, Sch Pharm, Fac Hlth Sci, Ga Rankuwa, South Africa