GENOTOXIC EFFECTS OF SOME FOODS AND FOOD COMPONENTS IN SWISS MICE

被引：0
|
作者：
BALACHANDRAN, B [1 ]
SIVASWAMY, SN [1 ]
SIVARAMAKRISHNAN, VM [1 ]
机构：
[1] CANC INST,DIV ISOTOPE,MADRAS 600020,INDIA
来源：
INDIAN JOURNAL OF MEDICAL RESEARCH SECTION B-BIOMEDICAL RESEARCH OTHER THAN INFECTIOUS DISEASES | 1991年 / 94卷
关键词：
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
A number of commonly consumed foods and food components in south India were screened for their genotoxic effects on Swiss mice. Salted, sundried and oil fried vegetables and fishes induced chromosomal aberrations, sperm head abnormalities and micronuclei production, which were comparable to the effect of the positive control viz., 20-methylcholanthrene. Spices like Cissus quadrangularis (an indigenous herb used in certain south Indian dishes) and pyrolysed cumin and aniseeds showed moderate effects. Calamus oil, widely used in pharmaceuticals was highly effective. All the three parameters of genotoxicity gave similar results.
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页码：378 / 383
页数：6
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