GENETICS OF TRANSITIONAL CELL-CARCINOMA

被引：4
|
作者：
KLEIN, EA
CHAGANTI, RSK
机构：
[1] Section of Urologic Oncology, Department of Urology, Cleveland Clinic Foundation, Cleveland, Ohio
[2] Laboratory of Cancer Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York
来源：
SEMINARS IN SURGICAL ONCOLOGY | 1992年 / 8卷 / 05期
关键词：
GENETICS; CHROMOSOMES; KARYOTYPES; TRANSITIONAL CELL CARCINOMA;
D O I：
10.1002/ssu.2980080503
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Several models of genetic events which define the origin and progression of human tumors have been elucidated over the last several years. These models suggest that the study of tumors at the level of both the chromosome and the gene can be useful in elucidating molecular events in tumor progression and in determining the biologic behavior of individual tumors. The genetics of transitional cell carcinomas are reviewed with emphasis on potential mechanisms of tumorigenicity and the clinical utility of genetic markers.
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页码：260 / 266
页数：7
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