ASSIGNMENT OF THE HUMAN GENE FOR BETA-MICROSEMINOPROTEIN (MSMB) TO CHROMOSOME-10 AND DEMONSTRATION OF RELATED GENES IN OTHER VERTEBRATES

被引：18

作者：

ULVSBACK, M ^{[1
]}

SPURR, NK ^{[1
]}

LUNDWALL, A ^{[1
]}

机构：

[1] IMPERIAL CANC RES FUND,CLARE HALL LABS,POTTERS BAR EN6 3LD,ENGLAND

来源：

GENOMICS | 1991年 / 11卷 / 04期

关键词：

D O I：

10.1016/0888-7543(91)90015-7

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The gene for β-microseminoprotein MSMB has been studied by DNA hybridization and molecular cloning techniques. Comparative analysis of restriction endonuclease digests of the cloned gene and of leukocyte DNA strongly suggested that the gene is present in a single copy in the haploid human genome. By Southern blot analysis of DNA from somatic cell hybrids, the gene was assigned to chromosome 10. The coding nucleotides of the human gene are separated into four exons by relatively large introns. A related gene might be present in other mammals, birds, and amphibians as revealed by DNA hybridization under conditions of low stringency. © 1991.

引用

页码：920 / 924

页数：5

共 37 条

[1] Assignment of the human beta-microseminoprotein gene (MSMB) to chromosome 10q11.2
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Sakai, H
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CYTOGENETICS AND CELL GENETICS, 1996, 72 (2-3): : 177 - 178
[2] COMPLETE SEQUENCE OF HUMAN VINCULIN AND ASSIGNMENT OF THE GENE TO CHROMOSOME-10
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (15) : 5667 - 5671
[3] ASSIGNMENT OF THE VASCULAR SMOOTH-MUSCLE ACTIN GENE ACTSA TO HUMAN CHROMOSOME-10
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BRUNS, G
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JAPANESE JOURNAL OF HUMAN GENETICS, 1990, 35 (02): : 145 - 150
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SHIRVAN, A
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BIOCHEMISTRY, 1994, 33 (22) : 6888 - 6901
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ZHANG, Y
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SOMATIC CELL AND MOLECULAR GENETICS, 1988, 14 (01) : 99 - 104
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HUMAN GENETICS, 1989, 83 (03) : 297 - 299
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HUMAN GENETICS, 1980, 55 (03) : 375 - 381
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AMERICAN JOURNAL OF HUMAN GENETICS, 1977, 29 (06) : A84 - A84
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FUJIBAYASHI, S
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WENGER, DA
AMERICAN JOURNAL OF HUMAN GENETICS, 1985, 37 (04) : 741 - 748
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WRIGHT, CE
SHOWS, TB
SOMATIC CELL GENETICS, 1979, 5 (04): : 503 - 517

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