Preparation of Bismuth (III) Citrate via Precipitation from the Solutions of Mineral Acids

Using the methods of XRD phase analysis, Raman and IR spectroscopy, thermogravimetry and chemical analysis the process of bismuth (III) citrate precipitation was investigated concerning the solutions of perchloric acid, nitric acid and hydrochloric acid under adding thereto a solution of citric acid or trisodium citrate. Conditions were determined with respect to the formation of compounds BiC6H5O7, BiOC6H7O7 center dot H2O and Bi-6(OH)(6)(C6H5O7)(4)center dot 6H(2)O. It was demonstrated that bismuth (III) citrate such as BiC6H5O7 used in medicine for the synthesis of pharmaceuticals and in microbiology the production of bacterial preparations are appropriate to obtain via the precipitation from nitric acid solutions from manufacturing bismuth compounds with adding citric acid; the molar ratio between citrate ions and bismuth ions in the solution should be equal to 1.1-1.2, the process temperature being of (60 +/- 5) degrees C.