PREDICTORS OF OUTCOME IN PROPHYLACTIC LITHIUM TREATMENT - A 2-YEAR PROSPECTIVE-STUDY

被引：94
|
作者：
AAGAARD, J
VESTERGAARD, P
机构：
[1] Clinical Department A, Institute of Psychiatric Demography, Psychopharmacology Research Unit
来源：
JOURNAL OF AFFECTIVE DISORDERS | 1990年 / 18卷 / 04期
关键词：
Non-adherence; Non-response; Prophylactic lithium;
D O I：
10.1016/0165-0327(90)90077-L
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The purpose of this study of 133 affective disorder patients consecutively referred to start prophylactic lithium treatment was to identify informative predictors of outcome. Non-adherence to treatment was mainly predicted by substance abuse and many earlier admissions. Non-response among the 78 patients adhering to lithium treatment was mainly predicted by female sex, young age and previously chronic course. The overall response rate was rather poor and an excess mortality rate was found. It is suggested that patients with substance abuse should not be offered prophylactic lithium treatment unless intensive control and support is practicable, and patients with a chronic course needa more effective treatment than lithium can offer. © 1990.
引用
收藏
页码：259 / 266
页数：8
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