SEPARATION OF CODEINE AND ITS BY-PRODUCTS BY CAPILLARY ZONE ELECTROPHORESIS AS A QUALITY-CONTROL TOOL IN THE PHARMACEUTICAL-INDUSTRY

被引：24

作者：

KORMAN, M ^{[1
]}

VINDEVOGEL, J ^{[1
]}

SANDRA, P ^{[1
]}

机构：

[1] STATE UNIV GHENT,DEPT ORGAN CHEM,KRIJGSLAAN 281 S4,B-9000 GHENT,BELGIUM

来源：

JOURNAL OF CHROMATOGRAPHY | 1993年 / 645卷 / 02期

关键词：

D O I：

10.1016/0021-9673(93)83397-B

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Capillary zone electrophoresis can be used for the detection of by-products in purified codeine. Separation of the by-products thebaine and 6-methylcodeine illustrates that small geometrical differences can be exploited to achieve effective separation. Examples of the capillary zone electrophoresis and micellar electrokinetic chromatography of codeine-containing drug formulations are presented.

引用

页码：366 / 370

页数：5

共 20 条

[1] Capillary zone electrophoresis separation of hydrolysates obtained from food industry by-products
Amarowicz, R
Zdunczyk, P
Flaczyk, E
[J]. CZECH JOURNAL OF FOOD SCIENCES, 2004, 22 (03) : 121 - 124
[2] CAPILLARY ELECTROPHORESIS IN CHEMICAL PHARMACEUTICAL QUALITY-CONTROL
PLUYM, A
VANAEL, W
DESMET, M
[J]. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 1992, 11 (01) : 27 - 32
[3] APPLICATIONS OF CAPILLARY ZONE ELECTROPHORESIS TO QUALITY-CONTROL
NIELSEN, RG
RICKARD, EC
[J]. ACS SYMPOSIUM SERIES, 1990, 434 : 36 - 49
[4] Quality control of piperaquine in pharmaceutical formulations by capillary zone electrophoresis
Zhang, Qin
Li, Yuan Fang
Huang, Cheng Zhi
[J]. TALANTA, 2008, 76 (01) : 44 - 48
[5] SEPARATION OF TETRACYCLINE AND ITS DEGRADATION PRODUCTS BY CAPILLARY ZONE ELECTROPHORESIS
ZHANG, CX
SUN, ZP
LING, DK
ZHANG, YJ
[J]. JOURNAL OF CHROMATOGRAPHY, 1992, 627 (1-2): : 281 - 286
[6] Separation of morphine and its oxidation products by capillary zone electrophoresis
Proksa, B
[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1999, 20 (1-2) : 179 - 183
[7] THE USE OF NEAR-INFRARED SPECTROSCOPY IN THE QUALITY-CONTROL LABORATORY OF THE PHARMACEUTICAL-INDUSTRY
PLUGGE, W
VANDERVLIES, C
[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1992, 10 (10-12) : 797 - 803
[8] GENERAL-GUIDELINES FOR HYGIENE IN THE DDR, A CONTRIBUTION TO QUALITY-CONTROL IN THE PHARMACEUTICAL-INDUSTRY
KEMPA, H
[J]. PHARMAZIE, 1987, 42 (06): : 425 - 425
[9] Capillary zone electrophoresis as a tool for the quality control of goldenseal extracts
Unger, M
Laug, S
Holzgrabe, U
[J]. ELECTROPHORESIS, 2005, 26 (12) : 2430 - 2436
[10] Quality control of pharmaceutical formulations of neuroleptic drugs by capillary zone electrophoresis
Pucci, V
Raggi, MA
Kenndler, E
[J]. JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 2000, 23 (01) : 25 - 34

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